DIVISION OF GIANT MITOCHONDRIA DURING RECOVERY FROM CUPRIZONE INTOXICATION
نویسندگان
چکیده
منابع مشابه
Division of Giant Mitochondria during Recovery from Cuprizone Intoxication
Giant mitochondria may be induced in mouse hepatocytes either by riboflavin deficiency (30) or by addition of the copper-chelating agent, cupri-zone (27, 28), to the diet. In both cases, the mitochondria attain enormous size, often exceeding the cell nuclei in diameter. It has recently been shown that the megam3tochondria resulting from riboflavin deficiency could be restored to normal dimensio...
متن کاملRestoration of hepatic mitochondria during recovery from carbon tetrachloride intoxication.
-During CC14 intoxication in rats, a disruption of hepatic mitochondrial structure and function occurs, which is characterized by a loss of respiratory activity, loss of phosphorylation coupled to respiration, and mitochondrial swelling, attended by loss of cristae structure. Within 15-25 hr, after full development of the mitochondrial lesion, the function and structure of the mitochondria are ...
متن کاملLiver giant mitochondria revisited.
AIMS To examine the correlation between the severity of alcohol induced liver damage and the presence of intracytoplasmic red bodies (defined as periodic acid-Schiff diastase negative, globular, hyaline cytoplasmic inclusions larger in size than the hepatocyte nucleolus). To investigate the incidence of intracytoplasmic red bodies (ICRBs) in non-alcoholic liver disease. METHODS Liver biopsy s...
متن کاملFGF2 and FGFR1 signaling regulate functional recovery following cuprizone demyelination
In demyelinating diseases, such as multiple sclerosis, remyelination offers the potential to recover function of viable denuded axons by restoring saltatory conduction and/or protecting from further damage. Mice with genetic reduction of fibroblast growth factor 2 (Fgf2) or Fgf receptor 1 (Fgfr1) exhibit dramatically improved remyelination following experimental demyelination with cuprizone. Th...
متن کاملResource translocation drives δ(13) C fractionation during recovery from disturbance in giant kelp, Macrocystis pyrifera.
Resource allocation and translocation are fundamental physiological functions for autotrophs. The mobilization and use of resources drive population dynamics by regulating growth and recovery of individuals, but also influences ecosystem-level processes such as primary productivity and carbon cycling. This study provides the first observation of translocation-driven gradients of δ(13) C in macr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1973
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.56.1.266